CERTIFICATE OF ANALYSIS
PRODUCT NAME:N,N'-Dicyclohexylcarbodiimide
PRODUCT NAME:N,N'-Dicyclohexylcarbodiimide
- INFORMATION OF N,N'-Dicyclohexylcarbodiimide:N,N'-Dicyclohexylcarbodiimide is an organic compound with the chemical formula C13H22N2 whose primary use is to couple amino acids during artificial peptide synthesis. Under standard conditions, it exists in the form of white crystals with a heavy, sweet odor. The low melting point of this material allows it to be melted for easy handling. It is highly soluble in dichloromethane, tetrahydrofuran,acetonitrile and dimethylformamide, but insoluble in water. The compound is often abbreviated DCC.
- REACTION:DCC is a dehydrating agent for the preparation of amides, ketones, nitriles. In these reactions, DCC hydrates to formdicyclohexylurea (DCU), a compound that is nearly insoluble in most organic solvents and insoluble in water. The majority of the DCU is thus readily removed by filtration, although the last traces can be difficult to eliminate from non-polar products. DCC can also be used to invert secondary alcohols.
- SAFTY:DCC is a potent allergen and a sensitizer, often causing skin rashes
- CAS NO:538-75-0
Chemical formula C13H22N2 Molar mass 206.33 g·mol−1 Appearance white crystalline powder Density 1.325 g/cm3, solid Melting point 34 °C (93 °F; 307 K) Boiling point 122 °C (252 °F; 395 K) (at 6 mmHg)